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Table 4 Effect of B. orthobotrys on body weight of rats in CFA induced arthritis (n = 5, Mean ± SEM)

From: Anti-arthritic activity of aqueous-methanolic extract and various fractions of Berberis orthobotrys Bien ex Aitch

Treatments Body weight gain (g)
Day 1 Day 5 Day 10 Day 15
Arthritic Control
(3 mL/kg)
262 ± 3.647 223 ± 3.906 218 ± 3.555 208 ± 4.534
Normal Control 269 ± 6.038ns 270 ± 5.544*** 270 ± 5.955*** 274 ± 6.112***
Standard Aspirin
(100 mg/kg)
243 ± 3.040** 246 ± 3.597*** 243 ± 2.926*** 245 ± 3.776***
Aqueous-methanolic extract (150 mg/kg) 265 ± 3.479ns 269 ± 4.176*** 277 ± 4.179*** 285 ± 4.320***
n-butanol fraction
(150 mg/kg)
259 ± 4.841ns 260 ± 5.109*** 261 ± 4.831*** 263 ± 4.802***
Ethyl acetate fraction
(150 mg/kg)
250 ± 2.922ns 251 ± 2.839*** 252 ± 2.379*** 253 ± 2.498***
Aqueous fraction
(150 mg/kg)
242 ± 2.205** 242 ± 2.227** 243 ± 2.577*** 246 ± 2.782***
  1. The statistical analysis was carried out using two way ANOVA followed by Bonferroni posttest. *** = p < 0.001, ** = p < 0.01, ns = p > 0.05 compared to arthritic control