Fig. 4

Effect of PFE on the levels of testosterone (a) and DHT (b) in serum and prostatic tissue. Individual data were obtained using an ELISA. NC (normal control group), corn oil injection (s.c.) + PBS administration (p.o.); BPH (control group), TP (3 mg/kg)/corn oil injection (s.c.) + PBS administration (p.o.); Fin (positive control group), TP (3 mg/kg)/corn oil injection (s.c.) + finasteride administration (10 mg/kg, p.o.); PFE (PFE-treated group), TP (3 mg/kg)/corn oil injection (s.c.) + PFE administration (200 mg/kg, p.o.). Data are presented as mean ± S.E.M. (n = 6). Significant differences at ^## P < 0.01 compared with the NC group. Significant differences at ^* P < 0.05 and ^** P < 0.01 compared with the BPH group. BPH, benign prostatic hyperplasia; DHT, dihydrotestosterone; Fin, finasteride; PBS, phosphate-buffered saline; PFE, Ponciri fructus extract; p.o., peroral; s.c., subcutaneously; TP, testosterone propionate