Table 1 Inclusion and Exclusion Criteria

Inclusion criteria

1. Age ≥ 18 years

2. Acute ischemic stroke diagnosed according to the Chinese Guideline for Diagnosis and Treatment of Ischemic Stroke (2014)

3. Admitted within 1 week after onset of stroke or within treatment time window for patients with thrombolysis therapy

4. Consent to participation in this study

Exclusion criteria

1. Patients with cerebral hemorrhage confirmed by CT imaging or MRI

2. Patients complicated by serious systemic diseases with an expected survival of less than 3 months

3. Patients cannot provide continuous follow-up information