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Table 5 Body weight, organ weight and serum liver enzyme profile of normal and 5 g/kg body weight of Xeniji treated mice for acute toxicity study

From: In vitro characterization and in vivo toxicity, antioxidant and immunomodulatory effect of fermented foods; Xeniji™

 

Normal

Xeniji (5 g/kg BW)

Day 0 BW (g)

20.21 ± 1.23

22.53 ± 1.29

Day 14 BW (g)

21.06 ± 0.73

23.02 ± 1.86

Liver weight (g)

1.41 ± 0.09

1.59 ± 1.86

Kidney weight (g)

0.51 ± 0.03

0.53 ± 0.04

Spleen weight (g)

0.14 ± 0.02

0.21 ± 0.01

Liver/BW ratio

0.0517

0.0537

Kidney/BW ratio

0.0187

0.0179

Spleen/BW ratio

0.0049

0.0069

ALT (U/L)

66.83 ± 2.33

63.40 ± 3.59

ALP (U/L)

69.75 ± 3.41

75.10 ± 6.77

AST (U/L)

108.32 ± 3.79

112.87 ± 3.41

Creatinine (μmol/L)

46.00 ± 3.56

46.00 ± 2.67

  1. No significant different was observed at p < 0.05 and p < 0.001