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Table 4 Effect of the methanol extract of H.micranthus leaves on excision wound model (n = 6)

From: Methanol leaves extract Hibiscus micranthus Linn exhibited antibacterial and wound healing activities

Post wounding days

Wound surface area (mean ± SEM) in mm2 and percentage of wound contraction

Ointment base

Nitrofurazone ointment (0.2%w/w)

Extract ointment (5% w/w each)

Extract ointment (10% w/w each)

0

220.60 ± 2.713 (0.0)

213.80 ± 7.971 (0.0)

227.80 ± 5.643 (0.0)

230.80 ± 2.871 (0.0)

2

180.80 ± 4.769 (18.04)

161.20 ± 7.010 (24.60)

166.00 ± 9.508 (27.13)

167.80 ± 12.395 (27.30)

4

145.40 ± 7.096 (34.09)

136.00 ± 6.782 (36.39)

119.20 ± 10.851 (47.67)

117.40 ± 9.765 (49.13)

6

113.80 ± 5.643 (48.41)

80.00 ± 8.390 (62.58)

76.20 ± 8.777* (66.55)

83.40 ± 10.028 (63.86)

8

70.80 ± 11.128 (67.91)

44.40 ± 4.261 (79.23)

36.60 ± 5.600* (83.93)

53.60 ± 7.467 (76.78)

10

34.60 ± 4.707 (84.32)

20.60 ± 2.088 (90.36)

16.80 ± 1.497* (92.63)

29.40 ± 5.400 (87.26)

12

19.80 ± 1.428 (91.02)

14.40 ± 2.400 (93.26)

10.80 ± 1.200* (95.26)

11.60 ± 2.400* (94.97)

14

9.40 ± 1.166 (95.74)

7.20 ± 3.200 (96.63)

2.40 ± 0.400 (98.95)

5.20 ± 1.068 (97.75)

16

6.60 ± 0.872 (97.00)

3.80 ± 2.835 (98.22)

1.60 ± 1.666 (99.30)

2.00 ± 1.095 (99.13)

  1. Values in parenthesis indicate percentage of wound contraction.* significant differences at p < 0.05 (statistical analysis was done by one-way analysis of variance (ANOVA) followed by Tukey’s test for multiple comparisons)