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Table 2 Diameter of zone of inhibition (mm) against bacteria by H.micranthus leaves extract

From: Methanol leaves extract Hibiscus micranthus Linn exhibited antibacterial and wound healing activities

Bacterial strain

Conc.μg/ml

p-value

Between

Mean zone of inhibition(mm) ± SEM

Extract

Cipr 5 μg

Ampi 10 μg

DMSO100μl

S. aureus

200

0.021

Extract-amp

18.33 ± 1.667

21.67 ± 1.202

25.33 ± 1.667

.00 ± .000

 

400

-

-

20.00 ± 1.555

 

800

-

-

22.67 ± 1.202

S.pneumoniae

200

-

-

20.67 ± 1.764

19.33 ± .333

21.00 ± .577

.00 ± .000

 

400

-

-

22.67 ± 1.202

 

800

0.016 0.03

Extract-cipr

Extract-amp

13.00 ± 1.528

S.pyogenes

200

-

-

.00 ± .000

23.33 ± .667

27.00 ± .577

.00 ± .000

 

400

-

-

14 ± .000

 

800

-

-

.00 ± .000

P.aeuruginosa

200

<0.001

Extract-cipr

.00 ± .000

27.00 ± .577

6.00 ± 6.00

.00 ± .000

 

400

0.037

Extract-amp

18.33 ± .333

 

800

<0.001

Extract-cipr

.00 ± .000

K.pneumoniae

200

0.013

Extract-amp

13.67 ± 1.856

18.00 ± 1.453

20.00 ± .577

.00 ± .000

 

400

0.040

Extract-amp

14.67 ± .667

 

800

-

-

16.33 ± 1.202

E.coli

200

-

-

.00 ± .000

23.67 ± 1.453

19.33 ± .333

.00 ± .000

 

400

-

-

.00 ± .000

 

800

-

-

.00 ± .000

P.mirabilis

200

-

-

.00 ± .000

30.00 ± .000

26.33 ± .333

.00 ± .000

 

400

-

-

.00 ± .000

 

800

-

-

.00 ± .000

  1. Conc- concentration of the extract; Cipr-ciprofloxacin; Amp -ampicillin; DMSO–Dimethyl sulphoxide, mm-millimeter, μg-microgram, μl-microlitre; ml-mililitre; SEM-standard error of the mean; ‘0’ - no zone of inhibition;(−) - no significant difference between extract and standard drugs. P-values <0.05 indicates significant difference between the extract and the standard drugs or positive controls. Values greater than 6 mm diameter of the well indicate some activity