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Table 6 Effect of Cynara scolymus leaves extracts on body weight gain of experimental groups of rats

From: Protective effects of Cynara scolymus leaves extract on metabolic disorders and oxidative stress in alloxan-diabetic rats

Groups of treatment Day1 Day 7 Day14 Day 21 Day 28
Cont 180.33 ± 0.57 182.13 ± 1.84 186.00 ± 1.09 197.50 ± 1.05 205.65 ± 4.92
Diab 181.48 ± 1.29ns 176.85 ± 2.74*** 173.22 ± 1.04*** 166.66 ± 2.08*** 154.66 ± 5.50***
Diab + Ethanol extract of leaves C. scolymus (200 mg/kg) 185.00 ± 6.24ns 195.39 ± 0.74###£ 199.41 ± 0.71###£££ 204.33 ± 1.90###£££ 207.56 ± 2.44###£££
Diab + Ethanol extract of leaves C. scolymus (400 mg/kg) 180.75 ± 0.55£££ 184.82 ± 0.23###£££ 188.04 ± 0.94###£££ 192.00 ± 2.64### 196.00 ± 1.00###
Diab + Acarbose (12 mg/kg) 189.70 ± 0.60# 192.76 ± 1.36### 193.20 ± 0.82### 194.13 ± 2.19### 197.16 ± 2.46###
  1. Diabetic rats were orally administered with the ethanol extract from leaves of C. scolymus and acarbose at the doses mentioned earlier for 28 days. Values are given as means ± SD (n = 8). *** p ≤ 0.001 were considered significant compared to control group; # p ≤ 0.05, ### p ≤ 0.001 were considered significant compared to diabetic rat.; £ p ≤ 0.05, £££ p ≤ 0.001 compared to diabetic rats treated with acarbose; ns: non-significant changes between diabetic treated groups vs. the control group after 28 days treatment