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Table 2 Effects of G. pensylvanicum and Allopurinol on Sur and XO active in Liver of PO-Induced Hyperuricemic Mice

From: Caffeoylquinic acid derivatives rich extract from Gnaphalium pensylvanicum willd. Ameliorates hyperuricemia and acute gouty arthritis in animal model

Groups

Dose (mg/kg)

Sur(μmol/L)

Liver XO (U/g protein)

Blank

-

5606.7 ± 1564.9

11.14 ± 1.06

Model

-

10,675.5 ± 3423.7**

54.28 ± 8.17##

Allopurinol

40

4280.1 ± 2229.5##

5.34 ± 0.65**

G. pensylvanicum extract

100

8388.6 ± 1546.3**

10.85 ± 1.53**

 

200

7288.3 ± 4615.0**

8.48 ± 0.85**

 

400

6012.9 ± 783.6**

6.09 ± 0.45**

  1. Data represent mean ± SEM for 10 mice; # p < 0.05, ## p < 0.01 compared with Blank group (independent samples t-test); * p < 0.05, ** p < 0.01 compared with Model group