Caffeoylquinic acid derivatives rich extract from Gnaphalium pensylvanicum willd. Ameliorates hyperuricemia and acute gouty arthritis in animal model

Table 1 Proposed compounds detected in G. pensylvanicum obtained by UPLC-ESI- MS/MS

Peak	Rt (min)	UV λ _max (nm)	*m/z*	MS/MS fragments	Proposed compound	Reference
1	2.41	213.7, 325.7	352.9	146.1	3-caffeoylquinic acid	[18,19,20,21,22]
2	2.64	322.7	352.9	249.2	4-caffeoylquinic acid	[18,19,20,21]
3	4.69	235.7, 325.7	367.0	308.9, 201.9, 175.3	feruloylquinic acid	[20, 21]
4	5.31	252.7, 345.7	447.1	435.7, 293.5, 106.6	luteolin-7-O-glucoside	[22]
5	5.71	219.7, 242.7, 324.7	515.2	428.8, 334.7, 94.9	1, 3-di-caffeoylquinic acid	[19,20,21]
6	5.89	218.7, 242.7, 326.7	515.3	490.9, 352.0, 179.1	1, 4-di-caffeoylquinic acid	[19, 20]
7	6.34	218.7, 243.7, 326.7	515.2	352.9, 173.0	3, 4-di-caffeoylquinic acid	[18,19,20,21]
8	6.61	244.7, 326.7	515.2	434.1, 346.3, 178.8	4, 5-di-caffeoylquinic acid	[18,19,20,21]
9	6.68	243.7, 327.7	601.0	288.4, 240.9	3-methoxyoxaloyl-1, 5-di-caffeoylquinic acid	[22]
10	7.03	243.7, 325.7	528.7	367.4, 172.8, 149.0	1-caffeoyl-3-feruloylquinic acid	[21]
11	7.54	243.7, 326.7	529.2	362.7, 349.2, 179.2	4-caffeoyl-3-feruloylquinic acid	[18, 21]
12	8.01	244.7, 328.7	529.0	374.0, 179.0, 155.6	4-caffeoyl-5-feruloylquinic acid	[18, 21]
13	8.21	243.7, 327.7	557.0	395.4, 233.3, 173.0	acetyldi-caffoylquinic acids	[22]
14	8.26	243.7, 326.7	615.4	453.5, 360.9, 235.8	succinoyl dicaffeoylquinic acids	[20]

ISSN: 2662-7671