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Fig. 7 | BMC Complementary and Alternative Medicine

Fig. 7

From: Effects of Karela (Bitter Melon; Momordica charantia) on genes of lipids and carbohydrates metabolism in experimental hypercholesterolemia: biochemical, molecular and histopathological study

Fig. 7

Protective effect of karela on changes in SREBP1c, HMG-CoAR and CYP7A1 expression induced by hypercholesterolemia in liver. Hypercholesterolemic rats were administered karela for 4 consecutive weeks. Total RNA was extracted from liver tissues and the expressions of SREBP1c, HMG-CoAR and CYP7A1 were analyzed by semi-quantitative RT-PCR analysis. Values are means ± SE of 10 rats. * P < 0.05 Vs control group; # P < 0.05 VS karela group and $ P < 0.05 Vs hypercholesterolemic group. Upper panels (a) are mRNA expression of examined genes. Lower columns (b) are densitometric analysis of gene expression for upper panels

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