Table 1 Minimum inhibitory concentration (MIC) and total antimycobacterial activity (TAA) and selectivity index (SI) of the eight selected acetone leaf extracts against Mycobacterium smegmatis, Mycobacterium fortuitum, Mycobacterium aurum. The SI and TAA values of the extracts were calculated from the cytotoxicity and percentage yield of the extracts results published in Elisha et al. [21]
M. smegmatis | M. fortuitum | M. aurum | |||||||
|---|---|---|---|---|---|---|---|---|---|
Plants | MIC (mg/ml) | TAA (ml/g) | SI | MIC (mg/ml) | TAA (ml/g) | SI | MIC (mg/ml) | TAA (ml/g) | SI |
Hypericum roeperianum | 0.63 | 190.42 | 0.11 | 1.25 | 95.97 | 0.05 | 1.25 | 95.97 | 0.05 |
Cremaspora triflora | 0.04 | 504.17 | 1.44 | 0.02 | 1008.33 | 2.87 | 0.08 | 252.08 | 0.72 |
Heteromorpha arborescens | 1.25 | 20.83 | 0.06 | 2.5 | 10.41 | 0.03 | 2.5 | 10.41 | 0.03 |
Bolusanthus speciosus | 1.25 | 18.43 | 0.04 | 1.25 | 18.43 | 0.04 | 2.5 | 9.21 | 0.02 |
Calpurnia aurea | 1.25 | 22.91 | 0.01 | 1.25 | 22.91 | 0.01 | 2.5 | 11.45 | 0.01 |
Maesa lanceolata | 0.16 | 695.21 | 0.01 | 0.31 | 358.82 | 0.01 | 2.5 | 44.49 | 0 |
Elaeodendron croceum | 2.5 | 35.99 | 0 | 1.25 | 71.97 | 0 | 2.5 | 35.99 | 0 |
Morus mesozygia | 0.63 | 29.31 | 0.06 | 0.31 | 59.57 | 0.13 | 2.5 | 7.39 | 0.02 |
Mean | 0.96 | NA | NA | 1.02 | NA | NA | 2.04 | NA | NA |
SD | 0.74 | NA | NA | 0.74 | NA | NA | 0.85 | NA | NA |
Streptomycin | 0.02 | NA | NA | 0.01 | NA | NA | 0.01 | NA | NA |
Rifampicin | 0.06 | NA | NA | 0.02 | NA | NA | 0.01 | NA | NA |