From: The modified Yi qi decoction protects cardiac ischemia-reperfusion induced injury in rats
 | Sham (n = 10) | I/R (1 week) | I/R (1 month) | ||||
---|---|---|---|---|---|---|---|
I/R (n = 10) | Low dose (n = 10) | High dose (n = 9) | I/R (n = 10) | Low dose (n = 10) | High dose (n = 9) | ||
HR (bpm) | 403.8 ± 20.8 | 354.8 ± 50.8 | 374.6 ± 26.5 | 443.6 ± 18.9 | 310.8 ± 22.4 | 355.7 ± 34.0 | 394.0 ± 41.8 |
RRI (ms) | 147.9 ± 6.8 | 185.8 ± 28.3 | 163.3 ± 11.7 | 136.3 ± 6.3 | 203.7 ± 22.4 | 179.7 ± 17.0 | 166.8 ± 29.1 |
SA P(mmHg) | 91.7 ± 3.4 | 80.8 ± 2.2* | 70.2 ± 13.3 | 68.1 ± 4.7 | 57.5 ± 2.1* | 72.4 ± 9.2†| 82.3 ± 3.3 |
DAP (mmHg) | 82.2 ± 2.8 | 50.0 ± 2.4* | 45.9 ± 11.2 | 54.3 ± 5.5 | 44.8 ± 1.0* | 50.5 ± 8.0 | 61.7 ± 3.8 |
MAP (mmHg) | 86.8 ± 2.3 | 61.9 ± 1.8* | 55.9 ± 11.7 | 60.7 ± 4.9 | 50.8 ± 0.9* | 59.0 ± 8.2 | 70.7 ± 3.6 |
PP (mmHg) | 9.5 ± 3.7 | 30.7 ± 2.4* | 24.3 ± 4.2 | 13.7 ± 3.2 | 12.7 ± 2.5 | 21.9 ± 2.2 | 20.5 ± 1.1 |
Pmax (mmHg) | 100.5 ± 7.5 | 87.6 ± 1.8* | 82.7 ± 10.5 | 98.3 ± 6.0†| 80.5 ± 2.1* | 90.8 ± 6.8†| 105.5 ± 3.1†|
Pmin (mmHg) | 2.8 ± 0.9 | 5.8 ± 0.4* | 5.5 ± 1.9 | 5.1 ± 3.8 | 7.8 ± 1.9* | 11.0 ± 3.4 | 2.4 ± 1.9†|
Pmean (mmHg) | 54.9 ± 2.8 | 42.8 ± 1.4* | 40.5 ± 7.2 | 49.8 ± 1.5†| 37.9 ± 0.9* | 41.9 ± 5.0†| 51.4 ± 1.7†|
Lvedp (mmHg) | 15.4 ± 2.3 | 41.9 ± 14.3* | 30.6 ± 13.2 | 41.0 ± 6.7 | 19.5 ± 3.7* | 18.6 ± 6.4 | 37.6 ± 3.4 |
P@dp/dtmax (mmHg) | 67.8 ± 8.6 | 67.0 ± 3.2 | 64.1 ± 11.6 | 83.9 ± 5.1 | 57.3 ± 1.2 | 64.8 ± 7.3 | 87.0 ± 3.5 |
P@-dp/dtmax (mmHg) | 69.5 ± 3.8 | 46.1 ± 1.1 | 46.7 ± 7.5 | 49.0 ± 2.6 | 47.0 ± 2.7 | 50.2 ± 5.8 | 50.3 ± 1.8 |
RPP | 33,425 ± 7359 | 30,482 ± 4066 | 31,914 ± 5969 | 43,830 ± 3697 | 25,151 ± 1953 | 33,544 ± 5012 | 42,123 ± 5324 |
dp/dtmax (mmHg/s) | 4943 ± 142 | 3637 ± 168* | 3247 ± 299 | 3744 ± 323†| 3452 ± 240* | 4078 ± 643†| 4125 ± 146†|
-dp/dtmax (mmHg/s) | −4479 ± 155 | −3893 ± 149* | −3223 ± 567 | −4167 ± 678†| −2753 ± 315* | −3161 ± 487†| 4528 ± 358†|
At (CFL)(CFU) | 102.8 ± 52.1 | 65.5 ± 108* | 40.8 ± 9.9 | 52.7 ± 11.3 | 37.9 ± 2.5* | 48.3 ± 9.7†| 72.9 ± 3.8†|
A1 (CFL)(CFU) | 9.7 ± 3.5 | 24.7 ± 9.5* | 7.5 ± 0.8 | 10.7 ± 1.5†| 9.0 ± 1.4 | 13.3 ± 3.1†| 13.9 ± 1.2†|
A2 (CFL)(CFU) | 12.5 ± 2.0 | 10.5 ± 1.2* | 8.6 ± 1.1 | 9.8 ± 1.5 | 10.4 ± 1.3* | 4.41 ± 2.9†| 12.4 ± 0.7†|
A3 (CFL)(CFU) | 10.4 ± 3.1 | 12.8 ± 0.7 | 10.5 ± 2.9 | 15.8 ± 3.9 | 7.6 ± 1.1* | 10.0 ± 2.0†| 18.3 ± 2.0†|
A4 (CFL)(CFU) | 70.2 ± 49.8 | 17.5 ± 2.1* | 14.2 ± 5.6 | 16.4 ± 5.7 | 10.9 ± 1.8* | 10.6 ± 2.1 | 28.4 ± 5.3†|
As (CFL)(CFU) | 22.2 ± 5.4 | 35.2 ± 9.1* | 16.1 ± 1.9†| 20.5 ± 2.8†| 19.4 ± 2.6* | 27.7 ± 5.9†| 26.2 ± 1.9†|
Ad (CFL)(CFU) | 80.6 ± 50.2 | 30.3 ± 2.2* | 24.7 ± 8.4 | 32.2 ± 9.5 | 18.5 ± 1.0* | 20.6 ± 4.1 | 45.7 ± 3.6†|
Smax (CRHL) | 160.4 ± 49.6 | 138.0 ± 89.4 | 214.9 ± 27.3 | 271.3 ± 43.9 | 239.4 ± 17.1* | 278.2 ± 68.4 | 263.7 ± 18.2†|
Smin (CRHL)(mmHg2/s2) | −202.2 ± 87.0 | −274.2 ± 25.9 | −248.3 ± 40.0 | −389.5 ± 56.9 | −240.7 ± 25.6 | −350.5 ± 88.0 | −392.3 ± 31.1†|
Dmax (CRHL)(mmHg2/s) | 155.9 ± 66.0 | 302.3 ± 25.5* | 210.1 ± 1.2 | 303.5 ± 98.8 | 168.6 ± 16.7 | 228.6 ± 57.6 | 348.7 ± 42.1†|
Dmin (CRHL)(mmHg2/s2) | −191.9 ± 16.8 | −276.1 ± 17.8* | −190.0 ± 43.6 | −315.7 ± 55.9 | −164.9 ± 18.7* | −211.3 ± 49.1†| −313.8 ± 34.1†|