TY - JOUR AU - Sun, Shuqin AU - Yang, Shuo AU - Dai, Min AU - Jia, Xiujuan AU - Wang, Qiyan AU - Zhang, Zheng AU - Mao, Yongjun PY - 2017 DA - 2017/06/13 TI - The effect of Astragalus polysaccharides on attenuation of diabetic cardiomyopathy through inhibiting the extrinsic and intrinsic apoptotic pathways in high glucose -stimulated H9C2 cells JO - BMC Complementary and Alternative Medicine SP - 310 VL - 17 IS - 1 AB - Apoptosis plays a critical role in the progression of diabetic cardiomyopathy (DC). Astragalus polysaccharides (APS), an extract of astragalus membranaceus (AM), is an effective cardioprotectant. Currently, little is known about the detailed mechanisms underlying cardioprotective effects of APS. The aims of this study were to investigate the potential effects and mechanisms of APS on apoptosis employing a model of high glucose induction of apoptosis in H9C2 cells. SN - 1472-6882 UR - https://doi.org/10.1186/s12906-017-1828-7 DO - 10.1186/s12906-017-1828-7 ID - Sun2017 ER -