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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Effects of sesamin on chondroitin sulfate proteoglycan synthesis induced by interleukin-1beta in human chondrocytes

Fig. 1

Effects of various IL-1β concentrations (2.5 to 10 ng/ml) pre-treatment on the gene and protein expression level of aggrecan (a, b), MMP-13 (c, d) and ADAMTS-4 (e, f) of HAC pellets. GAGs released in media during 21 days of culture with various concentrations of IL-1β (0 to 10 ng/ml) in 3-day pre-treated HAC pellets (g). The data presented are the mean ± S.D. of 3 independent cultures. Statistical significance compared to the untreated (control) * = p < 0.05, ** = p < 0.01

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