In vivo effect of Commiphora swynnertonii ethanolic extracts on Trypanosoma congolense and selected immunological components in mice

Table 1 Effect of extract of C. swynnertonii on parasitaemia in mice infected with T. congolense

		Parasitaemia level (logarithm number)/ml
Days	G2	G1	G5	G7	G8
0	5.4 ± 0.00	5.4 ± 0.00	5.46 ± 0.134	5.4 ± 0.00	5.4 ± 0.00
1	5.7 ± 0.3^*	6.84 ± 0.39	4.56 ± 2.56	7.14 ± 0.65	2.16 ± 2.96^*
2	6.98 ± 0.38	7.02 ± 0.94	4.62 ± 2.60^*	7.62 ± 0.34	3.66 ± 3.45^*
3	7.8 ± 0.3	7.28 ± 1.08	3.48 ± 3.19^*	7.98 ± 0.34	0.00 ± 0.00^*
4	8 ± 0.35	8.03 ± 0.29	4.5 ± 2.55^*	8.04 ± 0.25	0.00 ± 0.00^*
6	7.7 ± 0.62	7.5 ± 0.42	7.98 ± 0.16	7.88 ± 0.29	0.00 ± 0.00^*
12	8.1 ± 0.3	7.2 ± 0.55	6.72 ± 1.09	7.95 ± 0.17	0.00 ± 0.00^*
17	8 ± 0.17	7.95 ± 0.17	7.74 ± 0.13	7.95 ± 0.30	2.16 ± 2.96^*
35	8 ± 0.00	7.88 ± 0.29	8 ± 0.15	8.03 ± 0.15	3.18 ± 4.36

Values are mean ± STDEV; Day 0: the day treatment started; STDEV: standard deviation; G2, G1, G5: the groups that received ethanolic stem bark extract of C. swynnertonii at rate of 2000 mg/kg, 1500 mg/kg, 1000 mg/kg respectively, 8 hourly for 3 days; G7: infected-untreated group; G8: group that received diminazene diaceturate at rate of 3.5 mg/kg; Superscript “*”indicate significance at P < 0.05 compared to untreated group

ISSN: 2662-7671