Fig. 5

Histological sections of spleen from the mice in G12 treated with TME of C. swynnertonii (TME, 1500 mg/kg), 8 hourly intervals for three days consecutively. In (a), the white and red pulps are markedly reduced in size; the PALS has normal cellularity, lymphoid follicles and marginal zone are depleted. There is moderate apoptosis with karyorrhexis (arrows) and pyknosis of lymphocytes in (b). Magnifications, (a) 100 x; (b) 400 x