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Table 5 Antioxidant enzyme activities in liver tissue of APAP- treated rats, SOD (U/g tissue) and CAT (U/g tissue)

From: Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system

Treatment Dose (mg/kg) SOD
(U/g tissue)
CAT
(U/g tissue)
GSH (μM/mg protein)
Normal - 9.66 ± 0.38 114.80 ± 1.63 68.32 ± 1.19
10% DMSO + APAP - 3.99 ± 0.07a 91.36 ± 1.27a 29.77 ± 0.47
Silymarin + APAP 200 15.37 ± 0.35b 109.50 ± 4.69b 59.44 ± 0.95
MEDL + APAP 50 13.04 ± 0.16b 115.40 ± 2.37b 38.12 ± 0.71
250 11.29 ± 0.13b 120.30 ± 1.09b 53.11 ± 1.05
500 11.57 ± 0.33b 118.2 ± 0.81b 63.83 ± 2.03
  1. Values are expressed as means ± S.E.M. of six replicates
  2. aSignificant different as compared to normal control, P < 0.05
  3. bSignificant different as compared to negative control (10% DMSO + APAP), P < 0.05