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Table 5 Antioxidant enzyme activities in liver tissue of APAP- treated rats, SOD (U/g tissue) and CAT (U/g tissue)

From: Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system

Treatment

Dose (mg/kg)

SOD

(U/g tissue)

CAT

(U/g tissue)

GSH (μM/mg protein)

Normal

-

9.66 ± 0.38

114.80 ± 1.63

68.32 ± 1.19

10% DMSO + APAP

-

3.99 ± 0.07a

91.36 ± 1.27a

29.77 ± 0.47

Silymarin + APAP

200

15.37 ± 0.35b

109.50 ± 4.69b

59.44 ± 0.95

MEDL + APAP

50

13.04 ± 0.16b

115.40 ± 2.37b

38.12 ± 0.71

250

11.29 ± 0.13b

120.30 ± 1.09b

53.11 ± 1.05

500

11.57 ± 0.33b

118.2 ± 0.81b

63.83 ± 2.03

  1. Values are expressed as means ± S.E.M. of six replicates
  2. aSignificant different as compared to normal control, P < 0.05
  3. bSignificant different as compared to negative control (10% DMSO + APAP), P < 0.05
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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