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Table 4 Effects of different treatments on serum liver biomarkers of experimental rats

From: Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system

Treatment Dose (mg/kg) ALT (U/L) AST (U/L) ALP (U/L)
Control - 158.30 ± 2.86 95.13 ± 5.92 115.70 ± 6.99
APAP control (neg)   1714.00 ± 142.20a 2266.00 ± 340.40a 330.00 ± 42.35a
Silymarin +APAP (pos) 200 474.50 ± 82.17b 690.90 ± 146.60b 195.50 ± 11.06b
MEDL 50 225.90 ± 77.18b 309.50 ± 94.85b 252.20 ± 45.72
250 479.00 ± 204.10b 1184.00 ± 564.30b 228.20 ± 36.76b
500 445.10 ± 66.73b 786.60 ± 96.77b 350.30 ± 41.33
  1. Values are expressed as means ± S.E.M. of six replicates
  2. aSignificant different as compared to normal control, p < 0.05
  3. bSignificant different as compared to negative control, p < 0.05