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Table 4 Effects of different treatments on serum liver biomarkers of experimental rats

From: Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system

Treatment

Dose (mg/kg)

ALT (U/L)

AST (U/L)

ALP (U/L)

Control

-

158.30 ± 2.86

95.13 ± 5.92

115.70 ± 6.99

APAP control (neg)

 

1714.00 ± 142.20a

2266.00 ± 340.40a

330.00 ± 42.35a

Silymarin +APAP (pos)

200

474.50 ± 82.17b

690.90 ± 146.60b

195.50 ± 11.06b

MEDL

50

225.90 ± 77.18b

309.50 ± 94.85b

252.20 ± 45.72

250

479.00 ± 204.10b

1184.00 ± 564.30b

228.20 ± 36.76b

500

445.10 ± 66.73b

786.60 ± 96.77b

350.30 ± 41.33

  1. Values are expressed as means ± S.E.M. of six replicates
  2. aSignificant different as compared to normal control, p < 0.05
  3. bSignificant different as compared to negative control, p < 0.05