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Table 3 Effect of MEDL on body weight and liver weight in experimental rats

From: Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system

Treatment

Dose (mg/kg)

Body weight (BW) (g)

Liver weight (LW) (g)

LW/BW (%)

Control

-

208.70 ± 5.55

5. 85 ± 0.29

2.80 ± 0.07

APAP treated rats

 

219.50 ± 4.72

9.72 ± 0.15a

4. 44 ± 0.43a

Silymarin + APAP

200

200.00 ± 4.67

6.94 ± 0.24ab

3.47 ± 0.11ab

MEDL + APAP

50

218.07 ± 3.19

7.83 ± 0.88ab

3.59 ± 0.80ab

250

224.10 ± 3.41

6.16 ± 0.51b

2.75 ± 0.87b

500

218.64 ± 2.83

6.65 ± 0.87b

3.04 ± 0.88b

  1. Values are expressed as means ± S.E.M. of six replicates
  2. aSignificant different as compared to normal control, p < 0.05
  3. bSignificant different as compared to negative control, p < 0.05