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Table 3 Effect of MEDL on body weight and liver weight in experimental rats

From: Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system

Treatment Dose (mg/kg) Body weight (BW) (g) Liver weight (LW) (g) LW/BW (%)
Control - 208.70 ± 5.55 5. 85 ± 0.29 2.80 ± 0.07
APAP treated rats   219.50 ± 4.72 9.72 ± 0.15a 4. 44 ± 0.43a
Silymarin + APAP 200 200.00 ± 4.67 6.94 ± 0.24ab 3.47 ± 0.11ab
MEDL + APAP 50 218.07 ± 3.19 7.83 ± 0.88ab 3.59 ± 0.80ab
250 224.10 ± 3.41 6.16 ± 0.51b 2.75 ± 0.87b
500 218.64 ± 2.83 6.65 ± 0.87b 3.04 ± 0.88b
  1. Values are expressed as means ± S.E.M. of six replicates
  2. aSignificant different as compared to normal control, p < 0.05
  3. bSignificant different as compared to negative control, p < 0.05