Detection of antibacterial activities of Miswak, Kalonji and Aloe vera against oral pathogens & anti-proliferative activity against cancer cell line

Table 2 Mean zone of inhibition produced by herbal extract when used in combinations against S. aureus and C. albicans

Combination	S. aureus	C. albicans	P value
PM+EM	52 mm ± 0.7	61.5 mm ± 0.7	S*
PM+WM	46 mm ± 0	55 mm ± 0.7	S*
EM+WM	0 m	0 mm	NS
PK+EK	9 mm ± 0	8 mm ± 0	NS
WK+PK	8 mm ± 0.7	10 mm ± 0.7	NS
EK+WK	8 mm ± 0	7 mm ± 0	NS
PA+EA	7 mm ± 0	11 mm ± 0.7	NS
WA+PA	0 mm	8 mm ± 0	NS
EA+WA	0 mm	7 mm ± 0	NS
PM+PK	50 mm ± 1.4	66.5 mm ± 0.7	S*
PK+PA	10 mm ± 0.7	0 mm	NS
PA+PM	52 mm ± 0.7	65.5 mm ± 0.7	S*
EM+EK	0 mm	9 mm ± 0	NS
EK+EA	11 mm± 0.7	12 mm ± 0	NS
EA+EM	7 mm ± 0	10 mm ± 0	NS
WM+WK	0 mm	10 mm ± 0.7	NS
WK+WA	0 mm	11.5 mm ± 0.7	NS
WA+WM	0 mm	9.5 mm ± 0.7	NS
DMSO Negative control	0 mm	0 mm	−
Ciprofloxacin Positive control	26 mm ± 0	NA	−
Nystatin Positive Control	NA	17 mm ± 0	−

Petroleum ether Miswak + Ethanol Miswak(PM+EM), Petroleum ether Miswak + Water Miswak (PM+EM), Ethanol Miswak + Water Miswak (EM+WM), Petroleum ether Kalonji + Ethanol Kalonji (PK+EK), Water Kalonji+ Petroleum ether Kalonji (WK+PK), Ethanol Kalonji + Water Kalonji (EK+WK), Petroleum ether Aloe vera + Ethanol Aloe vera (PA+EA), Water Aloe vera + Petroleum ether Aloe vera (WA+PA), Ethanol Aloe vera + Water Aloe vera (EA+WA), Petroleum ether Miswak + Petroleum ether Kalonji (PM+PK), Petroleum ether Kalonji + Petroleum ether Aloe vera (PK+PA), Petroleum ether Aloe vera + Petroleum ether Miswak (PA+PM), Ethanol Miswak + Ethanol Kalonji (EM+EK), Ethanol Kalonji + Ethanol Aloe vera (EK+EA), Ethanol Aloe vera + Ethanol Miswak (EA+EM), Water Miswak + Water Kalonji (WM+WK), Water Kalonji + Water Aloe vera (WK+WA), Water Aloe vera + Water Miswak (WA+WM). NA: not applicable, S: Significant and NS: Non-significant
S* :Significant

ISSN: 2662-7671