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Table 6 The cytotoxic effect (expressed as % inhibition and IC50 values) of hexane and chloroform fractions of S. latifolius tested at 125, 250 and 500 μg/ml against Vero cells

From: Antioxidant activity, acetylcholinesterase inhibitory potential and phytochemical analysis of Sarcocephalus latifolius Sm. bark used in traditional medicine in Sudan

Code of extract

Concentration (ÎĽg/ml)

IC50 (ÎĽg/ml)

IC50

Inhibition % ± SD

500

250

125

Hexane

55.3 ± 0.04

50.4 ± 0.02

40.9 ± 0.03

277.8

>100

Chloroform

67.6 ± 0.08

55.0 ± 0.01

35.9 ± 0.05

224.9

>100

Control

95.3 ± 0.00

<30

  1. IC50 < 30 μg/ml: High toxic. Control = triton was used as positive control at 0.2 μg/ml. the maximum concentration used was 500 μg/ml