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Table 5 ROC Curve of weight gain, brain weight and age of eye opening between neuro-intoxicated, protected and therapeutically treated rat pups compared to healthy control

From: Postnatal treatment using curcumin supplements to amend the damage in VPA-induced rodent models of autism

Parameters Groups Area under the curve Cutoff value Sensitivity % Specificity %
Started weight (g) VPA 0.600 18.900 100.0% 40.0%
VPA-CUR 1.000 22.250 100.0% 100.0%
CUR 0.670 18.250 100.0% 60.0%
Final weight (g) VPA 0.700 25.450 60.0% 100.0%
VPA-CUR 0.915 77.550 80.0% 90.0%
CUR 0.585 71.300 100.0% 40.0%
Weight Gained VPA 0.640 8.700 60.0% 100.0%
VPA-CUR 0.800 60.200 60.0% 100.0%
CUR 0.530 52.700 100.0% 40.0%
Brain weight (g) VPA 0.640 1.415 80.0% 50.0%
VPA-CUR 0.905 1.477 100.0% 80.0%
CUR 0.590 1.364 90.0% 40.0%
Opening eyes after (Days) VPA 0.570 16.500 50.0% 100.0%
VPA-CUR 0.510 15.500 60.0% 70.0%
CUR 1.000 14.000 100.0% 100.0%