Groups | Fasting serum insulin (pM) | Insulinogenic index (pM insulin/mM glucose) | β-cell function (%) | |||
---|---|---|---|---|---|---|
Day 1 | Day 43 | Day 1 | Day 43 | Day 1 | Day 43 | |
Control (n = 11) | 170.3 ± 22.3 | 172.1 ± 27.5 | 37.21 ± 4.55 | 36.71 ± 3.72 | 136.25 ± 16.63 | 142.02 ± 21.38 |
Db (n = 8) | 34.4 ± 1.72 | 27.5 ± 3.4 | 1.95 ± 1.13 | 1.60 ± 0.47 | 20.17 ± 3.57 | 11.54 ± 1.56 |
AM (n = 6) | 39.5 ± 6.8 | 106.7 ± 12.0** | 2.27 ± 0.62 | 10.76 ± 1.21** | 21.07 ± 2.83 | 68.32 ± 4.56** |
Gb (n = 6) | 32.6 ± 6.8 | 87.7 ± 10.3* | 2.17 ± 0.89 | 12.32 ± 1.06** | 21.41 ± 3.11 | 74.85 ± 6.07** |