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Table 2 Effects of ECAP on plasma CTx and Osteocalcin contentrations in OVX mice

From: (−)-Epicatechin 3-O-β-d-allopyranoside prevent ovariectomy-induced bone loss in mice by suppressing RANKL-induced NF-κB and NFATc-1 signaling pathways

Drugs

Doses (mg/kg)

CTx(ng/ml)

Osteocalcin (ng/ml)

Sham

0

5.6 ± 1.2

27.9 ± 1.1

OVX + Vehicle

0

13.8 ± 1.1##

35.4 ± 1.3##

OVX + ECAP

50

11.8 ± 1.0*

31.3 ± 2.0**

OVX + ECAP

100

11.3 ± 1.1**

31.4 ± 1.4**

OVX + Alendronate

2.5

8.9 ± 1.6**

30.7 ± 1.3**

  1. ##P < 0.01 compared with shame group; *P < 0.05, **P < 0.01 compared with OVX + Vehicle group