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Table 2 Effects of ECAP on plasma CTx and Osteocalcin contentrations in OVX mice

From: (−)-Epicatechin 3-O-β-d-allopyranoside prevent ovariectomy-induced bone loss in mice by suppressing RANKL-induced NF-κB and NFATc-1 signaling pathways

Drugs Doses (mg/kg) CTx(ng/ml) Osteocalcin (ng/ml)
Sham 0 5.6 ± 1.2 27.9 ± 1.1
OVX + Vehicle 0 13.8 ± 1.1## 35.4 ± 1.3##
OVX + ECAP 50 11.8 ± 1.0* 31.3 ± 2.0**
OVX + ECAP 100 11.3 ± 1.1** 31.4 ± 1.4**
OVX + Alendronate 2.5 8.9 ± 1.6** 30.7 ± 1.3**
  1. ##P < 0.01 compared with shame group; *P < 0.05, **P < 0.01 compared with OVX + Vehicle group