Drugs | Doses (mg/kg) | Trabecular bone volume (%) | Number of trabeculae (No./mm) | Thickness of the trabeculae (μm) | Separation of trabeculae (μm) |
---|---|---|---|---|---|
Sham | 0 | 29.5 ± 1.9 | 2.8 ± 0.3 | 91.8 ± 2.9 | 212.0 ± 30.4 |
OVX + Vehicle | 0 | 20.6 ± 1.6## | 2.3 ± 0.2## | 80.1 ± 3.9## | 312.2 ± 25.6## |
OVX + ECAP | 50 | 24.3 ± 2.2* | 2.6 ± 0.2* | 84.4 ± 4.1 | 275.5 ± 15.4 |
OVX + ECAP | 100 | 24.5 ± 0.8** | 2.6 ± 0.1* | 85.4 ± 1.8* | 250.6 ± 25.8** |
OVX + Alendronate | 2.5 | 26.2 ± 2.0** | 2.7 ± 0.2** | 86.8 ± 4.3** | 227.2 ± 34.1** |