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Table 1 Effects of ECAP on the percentage of trabecular bone, number of trabeculae, thickness of the trabeculae and separation of trabeculae of the distal femoral metaphysis in OVX mice by microtomography analysis

From: (−)-Epicatechin 3-O-β-d-allopyranoside prevent ovariectomy-induced bone loss in mice by suppressing RANKL-induced NF-κB and NFATc-1 signaling pathways

Drugs Doses (mg/kg) Trabecular bone volume (%) Number of trabeculae (No./mm) Thickness of the trabeculae (μm) Separation of trabeculae (μm)
Sham 0 29.5 ± 1.9 2.8 ± 0.3 91.8 ± 2.9 212.0 ± 30.4
OVX + Vehicle 0 20.6 ± 1.6## 2.3 ± 0.2## 80.1 ± 3.9## 312.2 ± 25.6##
OVX + ECAP 50 24.3 ± 2.2* 2.6 ± 0.2* 84.4 ± 4.1 275.5 ± 15.4
OVX + ECAP 100 24.5 ± 0.8** 2.6 ± 0.1* 85.4 ± 1.8* 250.6 ± 25.8**
OVX + Alendronate 2.5 26.2 ± 2.0** 2.7 ± 0.2** 86.8 ± 4.3** 227.2 ± 34.1**
  1. ##P < 0.01 compared with shame group; *P < 0.05, **P < 0.01 compared with OVX + Vehicle group