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Table 5 Immunohistochemical expression of pro- and anti-apoptotic proteins in breast tumors treated and non-treated with Tualang honey

From: The anti-cancer effects of Tualang honey in modulating breast carcinogenesis: an experimental animal study

Groups  
Tumors 1
-ve control
2
(0.2 g/kg TH)
3
(1.0 g/kg TH)
4
(2.0 g/kg TH)
S.E
Total No of tumors developed. 35 16 20 15  
No. of Caspase-9 positive tumors (% expression) 16 (45.7%) 13 (81.3%) 14 (70.0%) 11 (73.3%) 1.20
No. of Apaf-1 positive tumors (% expression) 15 (42.9%) 15 (93.8%) 16 (80.0%) 11 (73.3%) 1.28
No. of FASLG positive tumors (% expression) 13 (37.1%) 0 0 0 3.75
No. of FADD positive tumors (% expression) 12 (34.3%) 0 0 0 3.64
No. of Bcl-xL positive tumors (% expression) 28 (80.0%) 9 (56.3%) 10 (50.0%) 10 (66.7%) 5.29
No. of ESR1 positive tumors (% expression) 26 (74.28%) 8 (50%) 11 (55%) 9 (60%) 4.86
  1. Kruskal-Wallis test; statistically significant differences between the groups, p < 0.05. Legend: TH Tualang Honey