Fig. 3

The gross morphology and histology of the breast tumors of rats in various TH-treated groups compared to the untreated negative control. The H/E stained sections were examined under light microscopy at X400 magnification. The majority of tumors in untreated negative control group were of grade III with increased heterogeneous nuclei formation and mitotic activity (plate A, arrow) compared to tumors in TH treatment groups which were of grade I and II (less aggressive) (Fig. 3.2); A = −ve control, B = 0.2 g/kg TH, C = 1.0 g/kg TH and D = 2.0 g/kg TH. Legends: TH = Tualang honey, MNU = 1-methyl-1-nitrosourea, −ve = Negative control (group that received tumor induction but no honey treatment)