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Table 2 Inhibitory concentration (IC50 in μg/mL) of extracts from roots, fruits, bark and leaves of Sarcocephalus pobeguinii and positive controls (trolox and ascorbic acid) or quercetin

From: Phytochemical analysis with free radical scavenging, nitric oxide inhibition and antiproliferative activity of Sarcocephalus pobeguinii extracts

Assay

IC50 in μg/mL

DPPH inhibition

ABTS inhibition

NO inhibition

RSP

854.65 ± 25.44

> 1000

> 100

FSP

234.48 ± 22.55

691.86 ± 33.41

84.43 ± 4.97

BSP

134.33 ± 1.02

400.08 ± 3.12

78.40 ± 3.47

LSP

7.98 ± 0.45a

15.35 ± 0.13a

46.09 ± 1.53a

Ascorbic acid

1.56 ± 0.57b

1.89 ± 0.36b

nd

Trolox

3.57 ± 0.26b

5.23 ± 0.98b

nd

Quercetin

nd

nd

5.07 ± 0.54b

  1. nd not determined, LSP Methanol extract from leaves of S. pobeguinii, RSP Methanol extract from roots of S. pobeguinii, FSP CH2Cl2/MeOH (1:2) extract from fruits of S. pobeguinii, BSP Methanol extract from bark of S. pobeguinii
  2. Data are presented as means of triplicate measurements ± standard error
  3. a significant difference between the extracts tested, (p Ë‚ 0.05)
  4. bsignificant difference between the extracts and the positive controls, (p Ë‚ 0.05)