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Table 7 Effects of test formulations on biochemical parameters in CFA-induced inflammation in rats

From: Effect of new polyherbal formulations DF1911, DF2112 and DF2813 on CFA induced inflammation in rat model

Groups

Total ALP activity in K.A. units

Albumin in g/dl

SGOT enzyme activity (U/ml)

SGPT enzyme activity (U/ml)

Total acid phosphatase activity in K.A. units

HC

7.25 ± 1.71***$$

6.61 ± 0.38***$$$

145 ± 14.2***$$

53.4 ± 5.2***

5.26 ± 0.27**$

NC

19.9 ± 1.27###&&

2.66 ± 0.43###&&&

255 ± 34.7###&

123 ± 2.7###&&&$$$

10.8 ± 0.59##&&

Diclo

8.98 ± 0.59**$

5.38 ± 0.29***

181 ± 17.9*

54.6 ± 3.1***

5.78 ± 0.45**

Dasha

17.9 ± 1.72##&

3.97 ± 0.27###

218 ± 17.7##

69 ± 8.2***

9.39 ± 1.66#

DF1911-LD

16.4 ± 1.83#

4.34 ± 0.42###*

211 ± 8#

83.9 ± 7.4#**&

8.34 ± 0.66

DF1911-MD

16.4 ± 2.62#

3.86 ± 0.36###&

202 ± 13

81.2 ± 10.2**

6.11 ± 0.7**

DF1911-HD

16.6 ± 2.83#

3.87 ± 0.16###&

228 ± 21.1##

78.1 ± 7.2***

9.39 ± 1.66#

DF2112-LD

12.8 ± 1.68

4.69 ± 0.58##**

206 ± 18.4#

76.7 ± 6.2***

6.41 ± 1.48*

DF2112-MD

13.8 ± 1.35

5.4 ± 0.28***$

199 ± 8.5

59.1 ± 5***

6.95 ± 0.42

DF2112-HD

13.4 ± 2.57

5.38 ± 0.33***

182 ± 12.9

62.4 ± 7.6***

6.27 ± 0.38*

DF2813-LD

17.3 ± 2.12##&

4.36 ± 0.29###*

217 ± 16.1#

88.3 ± 7.7##*&&

8.11 ± 0.77

DF2813-MD

19.1 ± 3.2##&

4.72 ± 0.33**##

205 ± 11

93.6 ± 10.1##&&

8.74 ± 0.37

DF2813-HD

16.5 ± 1.51#

5.12 ± 0.4***#

211 ± 5.8#

96 ± 7##&&

9.32 ± 0.76#

  1. HC healthy control, NC negative control, Diclo diclofenac sodium, Dasha Dashamoola Kwatha, DF Dashamoola formulation, LD lower dose, MD middle dose, HD higher dose, ALP alkaline phosphatase, SGOT serum glutamic-oxaloacetic transaminase, SGPT serum glutamic-pyruvic transaminase. Values are expressed as Mean ± SEM; n = 6. Data were analysed by One-Way ANOVA followed by Dunnett’s multiple comparison test. # = p < 0.05, ## = p < 0.01, ### = p < 0.001 when compared to HC; * = p < 0.05, ** = p < 0.01, *** = p < 0.001 when compared to NC; & = p < 0.05, && = p < 0.01, &&& = p < 0.001 when compared to Diclo; $ = p < 0.05, $$ = p < 0.01, $$$ = p < 0.001 when compared to Dasha