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Table 2 Histopathological alteration of the constipated mice after EXQ treatment

From: The immune-regulating effect of Xiao’er Qixingcha in constipated mice induced by high-heat and high-protein diet

Categories Model Group
Control Vehicle EXQ (0.75 g/kg) EXQ (1.5 g/kg) EXQ (3 g/kg)
Mucosa thickness (μm) HHPD 235.38 ± 30.19 190.78 ± 29.65# 262.05 ± 37.12* 264.11 ± 53.57* 259.74 ± 37.02*
HHPD + atropine 174.19 ± 34.58 167.81 ± 27.52 211.72 ± 9.68* 219.92 ± 49.80* 217.93 ± 34.63*
Muscle thickness (μm) HHPD 146.44 ± 24.67 80.20 ± 17.38## 106.03 ± 26.40 149.91 ± 18.93** 140.25 ± 37.16**
HHPD + atropine 48.90 ± 4.85 24.79 ± 10.73# 57.33 ± 19.95** 48.39 ± 6.68* 51.88 ± 21.31*
Submucosa thickness (μm) HHPD 46.37 ± 9.46 27.15 ± 5.46# 41.00 ± 14.75 54.65 ± 16.31** 48.03 ± 12.07*
  HHPD + atropine 44.84 ± 15.86 30.04 ± 5.64 31.60 ± 5.01 41.52 ± 15.22 41.78 ± 14.67
Number of goblet cell (ea) HHPD 376.17 ± 29.03 255.00 ± 31.03## 289.17 ± 27.09* 305.80 ± 28.47** 331.00 ± 23.82**
HHPD + atropine 210.86 ± 44.95 109.80 ± 33.49## 190.00 ± 52.35** 188.00 ± 36.99** 220.83 ± 34.14**
Number of crypt of lieberkuhn (ea) HHPD 31.20 ± 4.55 16.25 ± 2.22## 24.00 ± 6.04* 23.60 ± 4.45* 29.00 ± 5.79**
HHPD + atropine 27.00 ± 5.26 17.00 ± 3.32## 27.00 ± 8.49* 25.20 ± 6.72* 27.17 ± 5.38**
  1. # P < 0.05, ## P < 0.01 indicates significance when compared with the normal control group
  2. * P < 0.05, ** P < 0.01 indicates significance when compared with the vehicle treated constipation group