Skip to main content


Table 3 Effect of BuOH fraction (BuOH fr.) on urate induced synovitis in rats

From: Anti-Hyperuricemic, Anti-Inflammatory and Analgesic Effects of Siegesbeckia orientalis L. Resulting from the Fraction with High Phenolic Content

Group Number Dose (mg/kg p.o.) Score
Control 8 - 3.5 (2–4)
BuOH fr. 8 120 2 (1–3)*
Indomethacin 8 10 1 (1–1)**
  1. Inflammatory responses in the leg receiving sodium urate began 5 h after the injection, and continued to increase during 13 h (data not shown). Hyperalgesic responses were stable in all animals 2 h prior to the second drug administration. An anti-inflammatory agent was effective in this model. Values are expressed in median of score range (min – max). The Kruskal-Wallis test was performed, followed by the Mann-Whitney U test
  2. *p < 0.05, **p < 0.01 vs. control