Group | Number | Dose (mg/kg p.o.) | Score |
---|
Control | 8 | - | 3.5 (2–4) |
BuOH fr. | 8 | 120 | 2 (1–3)* |
Indomethacin | 8 | 10 | 1 (1–1)** |
- Inflammatory responses in the leg receiving sodium urate began 5 h after the injection, and continued to increase during 13 h (data not shown). Hyperalgesic responses were stable in all animals 2 h prior to the second drug administration. An anti-inflammatory agent was effective in this model. Values are expressed in median of score range (min – max). The Kruskal-Wallis test was performed, followed by the Mann-Whitney U test
- *p < 0.05, **p < 0.01 vs. control