|
Treatment
|
Dose (mg/kg, p.o)
|
Mean length of small intestinal (cm)
|
Mean distance traveled by charcoal (cm)
|
Peristalsis index (%)
|
% of inhibition
|
|---|
|
Control
|
–
|
55.60 ± 0.85
|
47.12 ± 0.87
|
84.74
|
–
|
|
Loperamide
|
3
|
55.83 ± 1.30
|
16.73 ± 0.42
|
29.97a3c3d3
|
64.49
|
|
ASLC
|
100
|
57.75 ± 1.02
|
36.05 ± 0.64
|
62.42a3d2e3
|
23.49
|
|
ASLC
|
200
|
57.00 ± 0.84
|
22.68 ± 0.47
|
39.80a3e3
|
51.86
|
|
ASLC
|
400
|
55.12 ± 1.67
|
15.85 ± 0.41
|
28.76a3
|
66.36
|
- All values are expressed as mean±standard error of the mean (SEM), (n = 6); Data was analyzed by one way ANOVA followed by Tukey post hoc test; acompared to the control (treated with distilled water), bto the standard drug, cto 100 mg/kg, dto 200 mg/kg, eto 400 mg/kg; 2
p < 0.01, 3
p < 0.001
-
ASLC aqueous stem extract of L. camara. Mice in the control group received distilled water (10 ml/kg)
