Treatment | Dose (mg/kg, p.o) | MWSIC (gm) | % inhibition by using MWSIC | MVSIC (ml) | % inhibition by using MVSIC |
---|
Control |  | 0.65 ± 0.017 | – | R2 = 0.790 | 0.50 ± 0.026 | – | R2 = 0.814 |
Loperamide | 3 | 0.16 ± 0.007a3c3d2e3
| 75.32 | 0.12 ± 0.007a3c3e2
| 76.77 |
ASLC | 100 | 0.41 ± 0.013a3d3e3
| 37.53 | 0.30 ± 0.013a3d3e3
| 38.73 |
ASLC | 200 | 0.24 ± 0.013a3e3
| 62.98 | 0.18 ± 0.019a3e3
| 64.65 |
ASLC | 400 | 0.07 ± 0.004a3
| 88.69 | 0.06 ± 0.003a3
| 88.89 |
- All values are expressed as mean±standard error of the mean (SEM), (n = 6); Data was analyzed by one way ANOVA followed by Tukey post hoc test; acompared to the control, bto the standard drug, cto 100 mg/kg, dto 200 mg/kg, eto400 mg/kg; 2
p < 0.01, 3
p < 0.001
-
ASLC aqueous stem extract of L. camara, MWSIC mean weight of small intestinal content, MVSIC mean volume of small intestinal content. Mice in the control group received distilled water (10Â ml/kg), R
2 coefficient of determination