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Table 2 Effect of the aqueous stem extract of L. camara on castor oil induced intraluminal fluid accumulation in mice

From: Evaluation of the anti-diarrheal activity of the aqueous stem extract of Lantana camara Linn (Verbenaceae) in mice

Treatment

Dose (mg/kg, p.o)

MWSIC (gm)

% inhibition by using MWSIC

MVSIC (ml)

% inhibition by using MVSIC

Control

 

0.65 ± 0.017

–

R2 = 0.790

0.50 ± 0.026

–

R2 = 0.814

Loperamide

3

0.16 ± 0.007a3c3d2e3

75.32

0.12 ± 0.007a3c3e2

76.77

ASLC

100

0.41 ± 0.013a3d3e3

37.53

0.30 ± 0.013a3d3e3

38.73

ASLC

200

0.24 ± 0.013a3e3

62.98

0.18 ± 0.019a3e3

64.65

ASLC

400

0.07 ± 0.004a3

88.69

0.06 ± 0.003a3

88.89

  1. All values are expressed as mean±standard error of the mean (SEM), (n = 6); Data was analyzed by one way ANOVA followed by Tukey post hoc test; acompared to the control, bto the standard drug, cto 100 mg/kg, dto 200 mg/kg, eto400 mg/kg; 2 p < 0.01, 3 p < 0.001
  2. ASLC aqueous stem extract of L. camara, MWSIC mean weight of small intestinal content, MVSIC mean volume of small intestinal content. Mice in the control group received distilled water (10 ml/kg), R 2 coefficient of determination