Fig. 6From: Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regenerationPI3K knockdown inhibited AOF extract-induced survival and proliferation. Schwann cell was transiently transfected with 5 nM PI3K siRNA for 1 h prior to treatment. After incubation with 100 μg/mL AOF extract for 24 h, cells were harvested and analyzed by immunoblotting. α-tubulin was used as a loading controlBack to article page