Fig. 3From: The Hippo signaling pathway: a potential therapeutic target is reversed by a Chinese patent drug in rats with diabetic retinopathyThe effect of XST on morphology of rat retinas. The retinas were fixed in formalin for trypsin digestion. a–c The vasculature in midretina. Scale bar: 50 μm. The images showed the acellular capillaries (black arrow), endothelial cells (green arrows) and pericytes(red arrow). d The acellular capillaries were counted and expressed as the total number/mm of retina area. There was a remarkable decrease in cellular capillaries in XST group. e The endothelial cells and pericytes were identified and counted. Then the ratio of endothelial cells number /pericytes number was calculated. XST administration improved the ratio of endothelial cells number /pericytes number. Data were represented as mean ± S.D. (n = 3–5).*: P < 0.05, **: P < 0.01, ***: P < 0.001, compared to DiabeticBack to article page