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Table 4 Top 15 commonly prescribed TCMs for treating HTN during study period

From: Association of traditional Chinese medicine therapy and the risk of dementia in patients with hypertension: a nationwide population-based cohort study

TCM name Ingredients or generic name Functions in TCM Frequency of prescriptions
N = 503,567 (%)
Average daily does (g) Average duration of prescription (day)
Tian-Ma-Gou-
Teng-Yin
Rhizoma Gastrodiae; Ramulus Uncariae Cum Uncis; Concha Haliotidis; Fructus Gardeniae Jasminoidis; Radix Scutellariae Baicalensis; Radix Cyathulae; Cortex Eucommiae Ulmoidis; Herba Leonuri; Herba Taxilli; Caulis Polygoni Multiflori; Sclerotium Poriae Cocos Calms the Liver, Extinguishes Wind, Clears Heat, Invigorates the Blood, Tonifies the Liver and Kidneys 24,823(4.9) 7.2 11.0
Dan-Shen Radix Salviae Miltiorrhizae Activates the Blood and dispels Blood Stasis, Cools the Blood and reduces abscesses, Nourishes the Blood and calms the Spirit 13,197(2.6) 3.0 11.7
Gou-Teng-San Ramulus Uncariae Cum Uncis; Radix Ginseng;
Sclerotium Poriae Cocos; Sclerotium Poriae Curcum; Radicem Pini; Radix Ophiopogonis;
Pericarpium Citri Reticulatae;
Rhizoma Pinelliae Preparatum; Radix Saposhnikoviae
Flos Chrysanthemi; Gypsum Fibrosum; Rhizoma Zingiberis Recens; Radix Glycyrrhizae
Clears Heat from the Liver channel, Descends Liver Yang, Extinguishes Liver Wind, Transforms Phlegm, Strengthens the Spleen, Enriches fluids 10,043(2.0) 7.4 9.5
Gou-Teng Ramulus Uncariae Cum Uncis Extinguishes Wind and alleviates spasms, Drains Liver Heat and pacifies Liver Yang, Releases the Exterior 8957(1.8) 2.8 11.2
Xia-Ku-Cao Spica Prunellae Clears Liver Fire and brightens the eyes, Clears Hot Phlegm and dissipates nodules 8153(1.6) 2.2 11.0
Zhi-Bai-Di-
Huang-Wan
Radix Rehmanniae Preparata; Fructus Corni Officinalis; Cortex Moutan; Rhizoma Dioscoreae Oppositae; Sclerotium Poriae Cocos; Rhizoma Alismatis Orientalis; Rhizoma Anemarrhenae Asphodeloidis; Cortex Phellodendri Chinensis Enriches Yin, Nourishes the Essence of the Liver and Kidneys, Reduces Deficiency Fire 6123(1.2) 5.1 11.9
Da-Huang Radix et Rhizoma Rhei Purges Heat, Loosens the bowels, Promotes Blood circulation, and removes Blood Stasis 5932(1.2) 1.1 11.4
Xue-Fu-Zhu-
Yu-Tang
Semen Pruni Persicae; Flos Carthami Tinctorii; Rhizoma Ligustici Chuanxiong; Radix Angelicae Sinensis; Radix Cyathulae; Fructus Aurantii; Radix Paeoniae Rubra; Radix Platycodi Grandiflori; Radix Bupleuri Chinensis; Radix Rehmanniae Glutinosae; Radix Glycyrrhizae Uralensis Invigorates the Blood, Dispels Blood Stasis, Spreads Liver Qi, Unblocks the channels, Stops pain 5758(1.1) 6.6 11.5
Chuan-Niu-Xi Radix Cyathulae Invigorates the Blood, Dispels Blood Stagnation, Promotes Urination and Drains Damp, Tonifies Liver and Kidney, Strengthens Tendon 5660(1.1) 2.3 12.4
Ge-Gen Radix Puerariae Dispels pathogenic factors from the superficial muscles to relieve fever, Promotes the production of body Fluid, Invigorates the Spleen Yang to stop diarrhea 5329(1.0) 1.5 10.7
Qi-Ju-Di-
Huang-Wan
Radix Rehmanniae Preparata; Fructus Corni Officinalis; Rhizoma Dioscoreae Oppositae; Rhizoma Alismatis Orientalis; Sclerotium Poriae Cocos; Cortex Moutan Radicis; Fructus Lycii Chinensis; Flos Chrysanthemi Morifolii Enriches Yin, Nourishes the essence of the Liver and Kidneys, Brightens eyes, improves vision, Enriches Blood 4286(0.9) 5.7 13.8
San-Qi Radix Notoginseng Arrests bleeding, Resolves Blood Stasis, Promotes the circulation of Blood 4254(0.8) 3.3 10.7
Tian-Ma Rhizoma Gastrodiae Stops Wind to relieve convulsion, Soothes the Liver, and suppresses hyperactive Liver Yang 4192(0.8) 1.6 11.1
Jia-Wei-Xiao-
Yao-San
Radix Bupleuri Chinensis; Radix Angelicae Sinensis; Radix Paeoniae Lactiflorae; Rhizoma Atractylodis Macrocephalae; Sclerotium Poriae Cocos; Radix Glycyrrhizae Uralensis; Cortex Moutan Radicis; Fructus Gardeniae Jasminoidis; Herba Menthae Haplocalycis; Rhizoma Zingiberis Recens Pacifies the Liver, Spreads Liver Qi, Strengthens the Spleen, Nourishes the Blood and Yin, Regulates menstruation, Sedates the Heart, Clears Heat 3984(0.8) 7.5 13.3
Jue-Ming-Zi Semen Cassiae Clears Liver Heat, Improves eyesight, Moistens the Intestines to relieve constipation 3949(0.8) 2.1 10.2