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Table 3 In vitro antiplasmodial activity of fractions from H. pubescens methanolic root extract

From: Anti-plasmodial activity of Norcaesalpin D and extracts of four medicinal plants used traditionally for treatment of malaria

Fraction Antiplasmodial activity
IC50 ± SD (μg/mL)
Cytotoxicity
CC50 ± SD (μg/mL)
LLC-MK2 cells
3D7 K1 IPC 5202 Battambang- Cambodia 2011 IPC 4912 Mondolkiri- Cambodia 2011
Fraction HPRM- 5 3.14 ± 0.18 5.23 ± 0.03 11.46 ± 0.2 8.61 ± 0.97 >200
Fraction HPRM- 7 1.20 ± 0.35 2.18 ± 0.95 2.52 ± 1.8 5.95 ± 2.79 >200
QN 0.052 ± 0.01 0.060 ± 0.01 0.074 ± 0.0 0.068 ± 0.005 >200
  1. HPRM-5 40% ethyl acetate/petroleum ether column fraction of H. pubescens methanolic root extract, HPRM-7 70% ethyl acetate/petroleum ether column fraction of H. pubescens methanolic root extract, QN quinine