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Table 2 In vitro anti-plasmodial activity and cytotoxicity of plant extracts

From: Anti-plasmodial activity of Norcaesalpin D and extracts of four medicinal plants used traditionally for treatment of malaria

Plant (Family) Part (extract) Antiplasmodial activity Cytotoxicity Selectivity index (SI)
IC50 on Dd2
(μg/mL ± SD)
CC50 on LLC-MK2 (μg/mL ± SD)
Erythrina schliebenii (Fabaceae) R (80% Ethanol) 1.87 ± 0.44 >200 >109
SB (H2O) 7.04 ± 0.72 >200 >28.4
Holarrhena pubescens (Apocynaceae) R (80% Ethanol) 2.43 ± 0.15 >200 >82.3
R (Methanol) 2.05 ± 0.56 >200 >97.6
Dissotis melleri Hook.f (Melastomataceae) AP (80% Ethanol) 8.23 ± 1.32 83.33 ± 3.31 10.1
Caesalpinia bonducella (Caesalpinaceae) R (Dichloromethane) 24.05 >200 >8.3
QN   0.06 ± 0.01   
Gleevec® (Imatinib)    19.43 ± 2.87  
  1. R root, SB stem bark, AP aerial parts (stem + leaves), QN quinine