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Table 5 Effect of oral dose of AHM and AHE for 7 days on brain tissue protein and oxidative stress markers

From: Anti-depressant and anxiolytic potential of Acacia hydaspica R. Parker aerial parts extract: Modulation of brain antioxidant enzyme status

Group

Protein

(μg/mg Tissue)

H2O2

(nM/min/mg Tissue)

Nitrite

(content μM/ml)

TBARS

(nM/min/mg protein)

Control (CMS)

1.25±0.032

5.854±0.011

78.12±0.499

7.575±0.573

AHM

1.372±0.033*

1.932±0.015***

42.59±0.552***

2.874±0.180***

AHE

1.367±0.015*

1.951±0.049***

41.72±0.650***

2.859±0.086***

Diazepam

1.363±0.018*

2.119±0.006***

49.94±0.770***

3.258±0.167***

Fluoxetine

1.37±0.027*

2.645±0.004***

50.60±0.32***

3.233±0.151***

  1. Values expressed as mean±SEM (n=6). *, ***: Significant difference at p < 0.05 and p < 0.0001 vs. control group respectively. (One way ANOVA followed by Tukey’s multiple comparison tests)