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Table 4 Effect of oral dose of AHM and AHE for 7 days on brain antioxidant status

From: Anti-depressant and anxiolytic potential of Acacia hydaspica R. Parker aerial parts extract: Modulation of brain antioxidant enzyme status

Group

SOD

(U/mg protein)

CAT

(U/min)

GR

(nM/min/mg protein)

GST

(nM/min/mg protein)

GSH

(μM/g tissue)

GPx

(nM/min/mg Protein)

Control (CMS)

0.79±0.027

9.035±0.09

108.7±1.09

108.9±1.105

12.36±0.490

63.2±1.027

AHM

1.15±0.037***

15.76±0.118***

154.9±0.96***

148.6±0.665***

20.55±0.280***

122.4±0.639***

AHE

1.14±0.049***

15.66±0.197***

155.6±0.439***

148.4±0.815***

20.66±0.237***

122.9±0.285***

Diazepam

1.04±0.025**

14.95±0.216***

141.2±1.00***

140.6±0.723***

18.59±0.44***

114.1±0.845***

Fluoxetine

1.06±0.053**

14.93±0.256***

140.3±1.55***

139.2±0.4623***

18.77±0.360***

115.9±1.29***

  1. Values expressed as mean±SEM (n=6). **, ***: Significant difference at p < 0.001 and p < 0.0001 vs. control group respectively. (One way ANOVA followed by Tukey’s multiple comparison tests)