Fig. 5

a The Kllsm4∆1 S. cerevisiae strain was transformed with mito-GFP, which targets GFP into the mitochondrial matrix. Cells were grown in glucose (SD) in the absence (NT) and in the presence of apple extracts at the indicated concentrations. The mitochondria morphology was evaluated by analyzing the GFP with an Axioskop2 fluorescence microscope (Carl Zeiss, Jena, Germany) equipped with a digital camera (micro-charge-coupled device). b Quantification of cell population showing fragmented mitochondria. Data represent the mean of three independent experiments. p-value: ** < 0.01; *** < 0.001