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Table 2 Linear regression analysis of CHHF with adipokine levels

From: Effects of cold sensitivity in the extremities on circulating adiponectin levels and metabolic syndrome in women

  Model 1 Model 2 Model 3
Traitsa Beta (95% CI) P value Beta (95% CI) P value Beta (95% CI) P value
All
 Adiponectin (μg/mL) 1.33 (1.16, 1.53) 4.44 × 10-5 1.23 (1.07, 1.40) 3.28 × 10-3 1.18 (1.02, 1.35) 2.32 × 10-2
 Leptin (ng/mL) −2.32 (−7.67, 1.42) 0.168 −1.49 (−5.06, 2.27) 0.521 1.10 (−3.19, 3.84) 0.59
 LAR −1.38 (−1.68, −1.14) 1.28 × 10-3 −1.22 (−1.48, 1.00) 4.62 × 10-2 −1.12 (−1.37, 1.09) 0.262
Men
 Adiponectin (μg/mL) 1.26 (−1.02, 1.60) 0.0686 1.21 (−1.04, 1.52) 0.113 1.13 (−1.13, 1.43) 0.332
 Leptin (ng/mL) 1.50 (−3.45, 7.80) 0.628 1.64 (−3.23, 8.66) 0.562 1.85 (−3.09, 10.5) 0.163
 LAR −1.27 (−1.77, 1.10) 0.164 −1.21 (−1.67, 1.15) 0.268 −1.09 (−1.53, 1.29) 0.636
Women
 Adiponectin (μg/mL) 1.40 (1.19, 1.66) 7.87 × 10-5 1.27 (1.08, 1.50) 3.17 × 10-3 1.23 (1.04, 1.45) 1.80 × 10-2
 Leptin (ng/mL) −4.38 (−22.2, 1.16) 0.0752 −2.35 (−2.51, 2.22) 0.311 −1.22 (−6.49, 4.39) 0.334
 LAR −1.48 (−1.89, −1.15) 2.03 × 10-3 −1.26 (−1.61, 1.01) 0.0611 −1.16 (−1.49, 1.10) 0.233
  1. aln-transformed: adiponectin and LAR
  2. Linear regression, adjusting (Model 1) for age, sex (in all), menopausal status (in women); (Model 2) model 1 covariates, diastolic blood pressure, triglycerides (ln-transformed); (Model 3) model 2 covariates, body mass index
  3. Abbreviations: CHHF cold hypersensitivity in the hands and feet, CI confidence interval, LAR leptin-to-adiponectin ratio