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Table 2 Linear regression analysis of CHHF with adipokine levels

From: Effects of cold sensitivity in the extremities on circulating adiponectin levels and metabolic syndrome in women

 

Model 1

Model 2

Model 3

Traitsa

Beta (95% CI)

P value

Beta (95% CI)

P value

Beta (95% CI)

P value

All

 Adiponectin (μg/mL)

1.33 (1.16, 1.53)

4.44 × 10-5

1.23 (1.07, 1.40)

3.28 × 10-3

1.18 (1.02, 1.35)

2.32 × 10-2

 Leptin (ng/mL)

−2.32 (−7.67, 1.42)

0.168

−1.49 (−5.06, 2.27)

0.521

1.10 (−3.19, 3.84)

0.59

 LAR

−1.38 (−1.68, −1.14)

1.28 × 10-3

−1.22 (−1.48, 1.00)

4.62 × 10-2

−1.12 (−1.37, 1.09)

0.262

Men

 Adiponectin (μg/mL)

1.26 (−1.02, 1.60)

0.0686

1.21 (−1.04, 1.52)

0.113

1.13 (−1.13, 1.43)

0.332

 Leptin (ng/mL)

1.50 (−3.45, 7.80)

0.628

1.64 (−3.23, 8.66)

0.562

1.85 (−3.09, 10.5)

0.163

 LAR

−1.27 (−1.77, 1.10)

0.164

−1.21 (−1.67, 1.15)

0.268

−1.09 (−1.53, 1.29)

0.636

Women

 Adiponectin (μg/mL)

1.40 (1.19, 1.66)

7.87 × 10-5

1.27 (1.08, 1.50)

3.17 × 10-3

1.23 (1.04, 1.45)

1.80 × 10-2

 Leptin (ng/mL)

−4.38 (−22.2, 1.16)

0.0752

−2.35 (−2.51, 2.22)

0.311

−1.22 (−6.49, 4.39)

0.334

 LAR

−1.48 (−1.89, −1.15)

2.03 × 10-3

−1.26 (−1.61, 1.01)

0.0611

−1.16 (−1.49, 1.10)

0.233

  1. aln-transformed: adiponectin and LAR
  2. Linear regression, adjusting (Model 1) for age, sex (in all), menopausal status (in women); (Model 2) model 1 covariates, diastolic blood pressure, triglycerides (ln-transformed); (Model 3) model 2 covariates, body mass index
  3. Abbreviations: CHHF cold hypersensitivity in the hands and feet, CI confidence interval, LAR leptin-to-adiponectin ratio