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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Withania somnifera leaf alleviates cognitive dysfunction by enhancing hippocampal plasticity in high fat diet induced obesity model

Fig. 1

Comparison of body weight, blood glucose, corticosterone and analysis of locomotor coordination tests. HFD regimen significantly increase the body weight in HFD and HFDE rats (a) compared to control rats. A significant reduction in the body weight was found in LFDE rats (a). Blood glucose levels remained unchanged between the groups (b). Corticosterone levels were significantly increased in HFD rats and restored to control levels in HFDE rats (c). During rotarod test, ASH treated HFD rats performed better than HFD rats during as assessed by latency to fall (d) and time spent (e) on rotarod. HFDE rats also performed better than HFD rats during narrow beam walk test as assessed by the paw slippage (f) and time taken (g) to transverse the beam indicating their intact locomotor functions. Values are expressed as ± SEM, *p < 0.05 LFD vs. HFD, LFDE and HFDE, # p < 0.05 LFDE and HFD rats, ¶ p < 0.05 HFDE vs. HFD rats, $signifies highly significant levels. Holm sidak post-hoc test after one-way ANOVA

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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