Fig. 3

Vasoconstrictor effect of (a) ​POL₄.Cr, (b) its ingredients, (c) verapamil and (d) phenylephrine (P.E) without and with phentolamine on basal tone of rat aortae. The data show mean ± SEM of 4 to 8 experiments using tissues of 4 to 5 animals.*p < 0.05, **p < 0.01 and***p < 0.001 vs. baseline effects, while ^# p < 0.05, ^## p < 0.01 and ^### p < 0.001 vs. vasoconstriction in the presence of phentolamine (Unpaired t-test). Abbreviations: POL₄.Cr, the crude extract of poly-herbal formulation; Ci, the crude extract of C. intybus; Gs, the crude extract of G. sylvestre; Ns, the crude extract of N. sativa; Tfg, the crude extract of T. foenum graecum