Fig. 1

The neurological function scores of the mice. Results are expressed as means ± SE. The PA was given after the disease onset. The mice in the Catalpol treated groups were given oral suspensions of 80 mg/kg, 40 mg/kg, 20 mg/kg respectively once a day for 40 days. The scores were measured in NC (×), EAE (●), EAE+ PA (6 mg/kg, ◆), EAE + Catalpol–H (80 mg/kg, ▲), EAE + Catalpol–M (40 mg/kg,△) and EAE + Catalpol–L (20 mg/kg, ■). Note: ^#P < 0.05, ^##P < 0.01 vs. EAE; ^◆P < 0.05, ^◆◆P < 0.01 vs. EAE+ PA; ^△P < 0.05 vs. EAE + Catalpol– M