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Table 3 The top 10 single Chinese herbs and Chinese herbal formula prescribed 2 years before and after HCC diagnosis by adjusting with person-year during 2002-2009 (n = 73,918)

From: Prescription frequency and patterns of Chinese herbal medicine for liver cancer patients in Taiwan: a cross-sectional analysis of the National Health Insurance Research Database

  Frequency of CHM prescribed (every visit) IRR P value
2 years before HCC diagnosis 2 years after HCC diagnosis   
n py IR n py IR
Single Chinese herbs Generic name (Chinese name)
3 Oldenlandia diffusa (Bai-Hua-She-She-Cao) 6,792 147,836 4.59 7,707 67,212 11.47 2.50 <0.001
8 Radix et Rhizoma Rhei (Da-Huan) 4,481 147,836 3.03 4,429 67,212 6.59 2.17 <0.001
5 Artemisia capillaris (Yin-Chen-Hao) 5,290 147,836 3.58 5,070 67,212 7.54 2.11 <0.001
4 Scutellaria baicalensis (Huang-Qin) 5,603 147,836 3.79 5,060 67,212 7.53 1.99 <0.001
7 Astragalus membranaceus (Huang-Qi) 4,677 147,836 3.16 4,042 67,212 6.01 1.90 <0.001
10 Polygonum multiflorum Thunb 3,994 147,836 2.7 3,398 67,212 5.06 1.87 <0.001
1 Salvia miltiorrhiza (Dan-shen) 9,558 147,836 6.47 7,827 67,212 11.65 1.80 <0.001
9 Puerariae Radix 4,148 147,836 2.81 3,383 67,212 5.03 1.79 <0.001
6 Fritillaria (Beimu) 5,246 147,836 3.55 4,093 67,212 6.09 1.72 <0.001
2 Corydalis yanhusuo (Yanhusuo) 7,902 147,836 5.35 5,909 67,212 8.79 1.64 <0.001
Chinese herbal formula (Chinese name)
6 Ping-Wei-San 5,093 147,836 3.45 4,563 67,212 6.79 1.97 <0.001
5 Xiang-Sha-Liu-Jun-Zi-Tang 5,963 147,836 4.03 5,304 67,212 7.89 1.96 <0.001
1 Jia-Wei-Xia-Yao-San 10,699 147,836 7.24 9,088 67,212 13.52 1.87 <0.001
2 Xiao-Chai-Hu-Tang 8,089 147,836 5.47 6,842 67,212 10.18 1.86 <0.001
8 Gan-Lu-Yin 4,962 147,836 3.36 4,040 67,212 6.01 1.79 <0.001
9 Shiee-Fuu-Jwu-Iu-Tang 4,731 147,836 3.2 3,633 67,212 5.41 1.69 <0.001
7 Sho-Yao-Gan-Cao-Tang 5,044 147,836 3.41 3,848 67,212 5.73 1.68 <0.001
10 Chuan-Chung-Cha-Tiao-San 4,688 147,836 3.17 3,379 67,212 5.03 1.59 <0.001
3 Long-Dan-Xie-Gan-Tang 6,803 147,836 4.6 4,835 67,212 7.19 1.56 <0.001
4 Shu-Jing-Hwo-Shiee-Tang 6,452 147,836 4.36 4,583 67,212 6.82 1.56 <0.001
  1. Py person-year, IR standardized incidence rate, IRR the ratio of standardized incidence rate