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Table 3 Influence of the aqueous and methanol extracts of Piptadeniastrum africanum on organs weight after CFA induced arthritis

From: Anti-arthritic property of crude extracts of Piptadeniastrum africanum (Mimosaceae) in complete Freund’s adjuvant-induced arthritis in rats

  Dose (mg/kg) Liver Spleen Kidney Thymus
Healthy control - 6.69 ± 0.16 0.60 ± 0.01 0.91 ± 0.03 0.63 ± 0.04
Arthritic control - 9.19 ± 0.29β 1.27 ± 0.04β 1.35 ± 0.08β 0.31 ± 0.01β
Indomethacin 5 7.45 ± 0.40a 0.81 ± 0.01a 0.98 ± 0.02a 0.54 ± 0.01a
Aqueous extract 200 7.85 ± 0.03 0.90 ± 0.05 1.12 ± 0.01 0.45 ± 0.04
400 6.61 ± 0.09b 0.77 ± 0.05a 0.91 ± 0.09b 0.54 ± 0.02a
Methanol extract 200 7.55 ± 0.30a 0.89 ± 0.01 1.03 ± 0.04a 0.59 ± 0.06b
400 6.55 ± 0.30c 0.74 ± 0.14b 0.93 ± 0.06b 0.62 ± 0.01b
  1. Each value represents the mean ± ESM for six animals and analyses by two-way ANOVA followed by Tukey post-hoc test, β P < 0.01 when compared to healthy control, a P < 0.05, b P < 0.01, c P < 0.001 when compared to arthritic control