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Table 2 Influence of the aqueous and methanol extracts of Piptadeniastrum africanum on haematological in CFA-induced arthritis in rats

From: Anti-arthritic property of crude extracts of Piptadeniastrum africanum (Mimosaceae) in complete Freund’s adjuvant-induced arthritis in rats

  Dose (mg/kg) Haemoglobin (g/dl) RBC (million/μl) Hematocrit (%) WBC (109/L) Platelet (109/L)
Healthy control - 14.35 ± 0.45 7.37 ± 0.10 40.80 ± 2.50 7.45 ± 0.45 813.00 ± 40.00
Arthritic control - 8.50 ± 0.20γ 3.99 ± 0.44β 26.75 ± 1.55α 13.25 ± 0.35γ 1815.00 ± 20.00γ
Indomethacin 5 11.60 ± 0.60a 6.05 ± 0.45 35.10 ± 2.20 10.00 ± 0.10b 1074.00 ± 26.00αc
Aqueous extract 200 12.05 ± 0.15a 5.90 ± 0.07 34.60 ± 0.90 8.80 ± 0.80b 1110.00 ± 21.00αc
400 12.15 ± 0.65a 6.53 ± 0.13a 36.85 ± 1.05a 8.40 ± 0.30b 1043.50 ± 4.50c
Methanol extract 200 12.15 ± 0.35a 6.13 ± 0.57 35.00 ± 3.00 10.85 ± 0.85α 1134.00 ± 45.00βc
400 12.45 ± 0.45a 6.89 ± 0.33a 38.60 ± 2.00a 8.85 ± 0.15b 919.00 ± 84.00c
  1. CFA complete Freund’s adjuvant, RBC red blood cell, WBC white blood cell, Hb haemoglobin, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration. Each value represents the mean ± ESM of six animals. α P < 0.05; β P < 0.01; γ P < 0.001 statistically significant compared to Healthy control. Each value represents the mean ± ESM of 6 animals. a P < 0.05; b P < 0.01; c P < 0.001 statistically significant compared to Arthritic control