Test compounds
|
aCC50 (μg/ml)
|
bIC50 (μg/ml)
|
---|
T. chebula 50% ethanolic extract
|
409.71 ± 47.70
|
0.01 ± 0.0002
|
Chebulagic acid
|
>200c
|
1.41 ± 0.51
|
Chebulinic acid
|
>200c
|
0.06 ± 0.002
|
Acyclovir
|
351.85 ± 48.80
|
29.04 ± 1.04
|
- Values in this table represent the mean ± SE of four independent experiments performed in duplicate
-
aCC50 was the concentration that showed viability of 50% of the Vero cells
-
bIC50 was the concentration that inhibited 50% of HSV-2 activity in direct anti- viral activity assay using Vero cells as host
-
c > 95% cells were viable at 200 μg/ml