Skip to main content

Table 2 GP-α and α-glucosidase inhibition activities of isolated compounds from B. javanica seeds

From: Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats

Compounds

Glycogen phosphorylase α (IC50 = μM)

α-glucosidase(IC50 = μM)

Vanillic Acid

ND1

ND1

Bruceine D

ND2

ND2

Bruceine E

ND2

ND2

Para-hydroxybenzoic acid

357.88 ± 0.07

649.07 ± 0.29

Luteolin

45.08 ± 0.04

26.41 ± 0.04

Protocatechuic acid

297.37 ± 0.13

368.74 ± 0.13

Gallic acid

214.38 ± 0.12

277.04 ± 0.12

Acarbose

-

145.83 ± 0.03

Caffeine

457.34 ± 0.05

-

  1. 1ND: IC50 values were not determined at the concentrations below 6 mM (α-glucosidase) and 12 mM (GP-α)
  2. 2ND IC50 values were not determined at the concentrations below 2.5 mM (α-glucosidase) and 5 mM (GP-α)